ABSTRACT
BACKGROUND: Non-alcoholic fatty liver disease is a chronic disease caused by the accumulation of fat in the liver related to overweight and obesity, insulin resistance, hyperglycemia, and high levels of triglycerides and leads to an increased cardiovascular risk. It is considered a global pandemic, coinciding with the pandemic in 2020 caused by the "coronavirus disease 2019" (COVID-19). Due to COVID-19, the population was placed under lockdown. The aim of our study was to evaluate how these unhealthy lifestyle modifications influenced the appearance of metabolic alterations and the increase in non-alcoholic fatty liver disease. METHODS: A prospective study was carried out on 6236 workers in a Spanish population between March 2019 and March 2021. RESULTS: Differences in the mean values of anthropometric and clinical parameters before and after lockdown were revealed. There was a statistically significant worsening in non-alcoholic fatty liver disease (NAFLD) and in the insulin resistance scales, with increased body weight, BMI, cholesterol levels with higher LDL levels, and glucose and a reduction in HDL levels. CONCLUSIONS: Lockdown caused a worsening of cardiovascular risk factors due to an increase in liver fat estimation scales and an increased risk of presenting with NAFLD and changes in insulin resistance.
Subject(s)
COVID-19 , Insulin Resistance , Non-alcoholic Fatty Liver Disease , Adult , COVID-19/epidemiology , Communicable Disease Control , Humans , Liver/metabolism , Longitudinal Studies , Non-alcoholic Fatty Liver Disease/epidemiology , Non-alcoholic Fatty Liver Disease/metabolism , Pandemics , Prospective Studies , Risk FactorsABSTRACT
In December 2019, 27 cases of pneumonia were reported in Wuhan. In 2020, the causative agent was identified as a virus called SARS-CoV-2. The disease was called "coronavirus disease 2019" (COVID-19) and was determined as a Public Health Emergency. The main measures taken to cope with this included a state of lockdown. The aim of this study was to assess how the unhealthy lifestyles that ensued influenced different parameters. A prospective study was carried out on 6236 workers in a Spanish population between March 2019 and March 2021. Anthropometric, clinical, and analytical measurements were performed, revealing differences in the mean values of anthropometric and clinical parameters before and after lockdown due to the pandemic, namely increased body weight (41.1 ± 9.9-43.1 ± 9.9), BMI (25.1 ± 4.7-25.9 ± 4.7), and percentage of body fat (24.5 ± 9.1-26.9 ± 8.8); higher total cholesterol levels, with a statistically significant increase in LDL levels and a reduction in HDL; and worse glucose levels (90.5 ± 16.4-95.4 ± 15.8). Lockdown can be concluded to have had a negative effect on health parameters in both sexes in all age ranges, causing a worsening of cardiovascular risk factors.
Subject(s)
COVID-19 , Glucose , Adult , Blood Pressure , COVID-19/epidemiology , Communicable Disease Control , Female , Humans , Lipids , Longitudinal Studies , Male , Pandemics , Prospective Studies , SARS-CoV-2ABSTRACT
Desde la identificación del virus SARS-CoV-2 como causante de la enfermedad y pandemia COVID-19, el diagnóstico de los infectados, el control de los grupos de riesgo y la inmunidad de la población han sido los principales objetivos de la comunidad científica. Son imprescindibles las pruebas de laboratorio para diagnosticar a los contagiados, determinar el estado y evolución de la enfermedad en los pacientes con clínica y la inmunidad que ha desarrollado cada grupo social. Dependiendo de los resultados de las distintas pruebas de laboratorio COVID-19, los profesionales sanitarios indican diferentes actuaciones. Los Odontólogos debemos indicar la realización de tratamientos dentales basándonos en los resultados de las pruebas de laboratorio COVID-19 dado el alto riesgo de diseminación y contagio que conllevan nuestros tratamientos. Since the identification of the SARS-CoV-2 virus as the cause of the disease and the COVID-19 pandemic, the diagnosis of the infected population, the control of risk groups, and the immunity of the population have been the main objectives of the scientific community. Laboratory tests are essential to diagnose infected population, determine the status and evolution of the disease in patients with symptoms, and the immunity that each social group has developed. Depending on the results of the different COVID-19 laboratory tests, healthcare professionals indicate different actions and treatments. Dentists must take into account the results of COVID-19 laboratory tests of their patients as input before to the performance of any dental treatments, given the high risk of spread and contagion that dental treatments entail.